Dendrimer mediated targeted delivery of sinomenine for the treatment of acute neuroinflammation in traumatic brain injury
Rishi Sharma, Siva P. Kambhampati, Zhi Zhang, Anjali Sharma, Samuel Chen, Erica I. Duh, Sujatha Kannan, Mark O.M. Tso, Rangaramanujam M. Kannan
Topics & Concepts
NeuroinflammationSinomenineInflammationMicrogliaPharmacologyBlood–brain barrierMedicineNeuroprotectionTraumatic brain injuryDrug deliveryOxidative stressDrugSystemic administrationImmunologyChemistryCentral nervous systemInternal medicineBiologyIn vivoOrganic chemistryPsychiatryBiotechnologyDendrimers and Hyperbranched PolymersRNA Interference and Gene DeliveryParaquat toxicity studies and treatments