Ebselen alleviates white matter lesions and improves cognitive deficits by attenuating oxidative stress via Keap1/Nrf2 pathway in chronic cerebral hypoperfusion mice
Fuxing Dong, Weixing Yan, Qiqi Meng, Xueli Song, Bing Cheng, Yaping Liu, Ruiqin Yao
Topics & Concepts
Oxidative stressWhite matterHyperintensityPathologyInternal medicineCerebral blood flowLipid peroxidationEbselenMedicineGlutathione peroxidaseEndocrinologyChemistrySuperoxide dismutaseMagnetic resonance imagingRadiologyNeurological Disease Mechanisms and TreatmentsBiochemical effects in animalsNeurological Disorders and Treatments