Manganese exposure caused reproductive toxicity of male mice involving activation of GnRH secretion in the hypothalamus by prostaglandin E2 receptors EP1 and EP2
Fengdi Wu, Haibo Yang, Yanan Liu, Xinxin Yang, Bin Xu, Wei Liu, Zhaofa Xu, Yu Deng
Topics & Concepts
Prostaglandin E2 receptorEndocrinologyReceptorInternal medicineHypothalamusSecretionBiologyProstaglandinHormoneProstaglandin E2Paracrine signallingGonadotropin-releasing hormoneEndocrine systemMedicineLuteinizing hormoneAgonistHypothalamic control of reproductive hormonesSperm and Testicular FunctionPharmacological Effects and Toxicity Studies