Tunable Fe3O4 Nanorods for Enhanced Magnetic Hyperthermia Performance
Yongxiu Yang, Mengwei Huang, Jinmei Qian, Daqiang Gao, Xiaolei Liang
Abstract
Abstract Magnetic hyperthermia is one of the most promising techniques for treating gynecological cancer, where magnetite (Fe 3 O 4 ) is the most common nanomaterial used as a magnetic hyperthermia agent. Here, we demonstrate that optimal Fe 3 O 4 nanorods (NRs) can act as a magnetic hyperthermia agent with higher specific absorption rate (SAR), which is mostly attributed to their enhanced surface anisotropy. As a result, Fe 3 O 4 NRs could effectively hinder the growth of gynecological cancer cells in nude mice models, again demonstrating its good magnetic heating properties. These results provide a powerful basis for the development of an ideal magnetic hyperthermia agent with enhanced SAR, thereby effectively treating gynecological cancer in clinical practice.