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Quasi‐MOF‐Engineered MnO<i><sub>x</sub></i>/CeBTC Multinanozyme as a Robust Self‐Cascade ROS Generator toward Antibacterial Face Mask

Yuqi Meng, Ruiting Han, Qing Tian, Yao Chen, Lianbing Zhang

2024Advanced Healthcare Materials21 citationsDOIOpen Access PDF

Abstract

Abstract It is of great importance to endow personal protective equipments with bactericidal property combating against infected pathogens. Nanozyme that can generate reactive oxygen species (ROS) in an enzyme‐catalytic manner is regarded as a novel and promising nanobactericide. But until now, very rare of them is designed specifically for personal protective equipments. In this study, a multinanozyme of manganese oxide supported on Ce‐containing MOF (CeBTC) is constructed with post‐engineering via a quasi‐metal‐organic framework (MOF) strategy (denoted as MnO x /q‐CeBTC). The strategy enables a full exposure of the metal cluster nodes, introduction of new active Mn─O─Ce bonds and strengthens interaction between the metal nodes and the guest oxide. As an advanced multinanozyme, the MnO x /q‐CeBTC exhibits excellent multiple enzymatic activities at low temperature, and enables abundant and self‐cascade ROS generation without H 2 O 2 addition. This empowers it with high efficiency in bacteria killing, which is also reflected when incorporated into face mask to combat against pathogen invasion even at low temperature. The results achieved in this work provide guidance for rational design of effective bactericide based on nanozyme and broaden their application in personal protective equipment and other fields.

Topics & Concepts

Rational designManganeseMaterials scienceReactive oxygen speciesNanotechnologyMetalCatalysisOxideCascadeCombinatorial chemistryChemistryChemical engineeringOrganic chemistryEngineeringBiochemistryMetallurgyAdvanced Nanomaterials in CatalysisNanoplatforms for cancer theranosticsAdvanced biosensing and bioanalysis techniques
Quasi‐MOF‐Engineered MnO<i><sub>x</sub></i>/CeBTC Multinanozyme as a Robust Self‐Cascade ROS Generator toward Antibacterial Face Mask | Litcius