A Phase II Trial of Pevonedistat and Docetaxel in Patients With Previously Treated Advanced Non–Small-Cell Lung Cancer
Angel Qin, Leah Wells, Binu Malhotra, Shirish M. Gadgeel, Bryan J. Schneider, Nithya Ramnath, John D. Rice, Gregory P. Kalemkerian
Topics & Concepts
DocetaxelCullinMedicineLung cancerNEDD8NeddylationRamucirumabCancer researchCancerOncologyInternal medicinePharmacologyBiologyBiochemistryUbiquitinUbiquitin ligaseGeneUbiquitin and proteasome pathways14-3-3 protein interactionsProtein Degradation and Inhibitors