Litcius/Paper detail

Severus detects somatic structural variation and complex rearrangements in cancer genomes using long-read sequencing

Ayse G. Keskus, Asher Bryant, Tanveer Ahmad, Byunggil Yoo, Sergey Aganezov, Anton Goretsky, Ataberk Donmez, Lisa A. Lansdon, Isabel Rodriguez, Jimin Park, Yuelin Liu, Xiwen Cui, Joshua Gardner, Brandy McNulty, Samuel Sacco, Jyoti Shetty, Yongmei Zhao, Bao Tran, Giuseppe Narzisi, Adrienne Helland, Daniel E. Cook, Pi-Chuan Chang, Alexey Kolesnikov, Andrew Carroll, Erin K. Molloy, Chengpeng Bi, Adam Walter, Margaret Gibson, Irina Pushel, Erin Guest, Tomi Pastinen, Kishwar Shafin, Karen H. Miga, Salem Malikić, Chi‐Ping Day, Nicolas Robine, S. Cenk Şahinalp, Michael Dean, Midhat S. Farooqi, Benedict Paten, Mikhail Kolmogorov

2025Nature Biotechnology24 citationsDOIOpen Access PDF

Topics & Concepts

Structural variationSomatic cellGenomeBiologyGeneticsVariation (astronomy)DNA sequencingComputational biologyEvolutionary biologyDNAGenePhysicsAstrophysicsCancer Genomics and DiagnosticsGenomics and Rare DiseasesGenomics and Phylogenetic Studies
Severus detects somatic structural variation and complex rearrangements in cancer genomes using long-read sequencing | Litcius