A ratiometric fluorescent probe for detecting the endogenous biological signaling molecule superoxide anion and bioimaging during tumor treatment
Yue Wang, Xiaoyan Wang, Li Zhang, Yan Huang, Liyan Bi, Changjun Lv, Lingxin Chen
Abstract
A fluorescent probe for O<sub>2</sub>˙<sup>−</sup> detection during tumor treatment revealed that curcumin can sensitize cisplatin for tumor treatment by inducing severe O<sub>2</sub>˙<sup>−</sup> burst.
Topics & Concepts
FluorescenceCurcuminEndogenySuperoxideCisplatinIonMoleculeBiophysicsChemistryMaterials scienceCancer researchPhotochemistryBiochemistryMedicineChemotherapyBiologyOrganic chemistryOpticsInternal medicineEnzymePhysicsMolecular Sensors and Ion DetectionLanthanide and Transition Metal ComplexesMetal complexes synthesis and properties