Photosensitized Imino-Thiocyanation of Alkenes
Cong Huang, Zhenzhen Xie, Jie Gao, Xiang Mei, Hao‐Yue Xiang, Kai Chen, Hua Yang
Abstract
A metal-free photosensitized 1,2-imino-thiocyanation of olefins has been established by using the easily accessible bifunctional reagent S -cyano- N -(diphenylmethylene) thiohydroxylamine. A wide range of olefins were successfully transformed into the corresponding β-iminothiocyanates in moderate to high yields. This protocol stands out for its metal-free nature, broad substrate compatibility, and high atom and step economy, providing an effective strategy for assembling β-amino thiocyanate-containing scaffolds.
Topics & Concepts
ChemistryCombinatorial chemistrySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsSynthesis and Catalytic Reactions