Litcius/Paper detail

Insights into Salt Handling and Blood Pressure

David H. Ellison, Paul Welling

2021New England Journal of Medicine100 citationsDOI

Abstract

Salt intake is associated with blood pressure, but the relationship is complex. This review highlights the interplay among renal salt transport, salt storage in the skin and interstitium, vascular adaptation to changes in the salt concentration, and neurohormonal signaling.

Topics & Concepts

Salt (chemistry)Blood pressureChemistryInternal medicineMedicineKidneySalt solutionAdaptation (eye)EndocrinologyFood scienceSodium Intake and HealthRenal function and acid-base balanceThermoregulation and physiological responses