Microglia and Reactive Oxygen Species Are Required for Behavioral Susceptibility to Chronic Social Defeat Stress
Christopher A. Guevara, Pamela Del Valle, Cynthia Mercedes
Abstract
Psychosocial stress occurs in response to a potentially life-threatening interaction and leaves a lasting impact that can be detected and measured physiologically and psychologically. This type of stress is a major risk factor for the development of psychopathologies like depression and anxiety ([
Topics & Concepts
Social defeatDepression (economics)AnxietyPsychosocialPsychologyChronic stressReactive oxygen speciesClinical psychologyStress (linguistics)MicrogliaSocial stressNeuroscienceMedicinePsychiatryBiologyInflammationImmunologyGeneticsLinguisticsPhilosophyEconomicsMacroeconomicsNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disordersStress Responses and Cortisol