New ruthenium(<scp>ii</scp>) catalysts enable the synthesis of 2-amino-4<i>H</i>-chromenes using primary alcohols <i>via</i> acceptorless dehydrogenative coupling
Tamilthendral Veerappan, Rengan Ramesh, J.G. Małecki
Abstract
Direct access to a diverse range of 2-amino-4 H -chromenes was established in excellent yields through a one-pot multicomponent ADC reaction of benzyl alcohols catalysed by p -cymene Ru( ii ) complexes under additive/promotor-free conditions.
Topics & Concepts
ChemistryRutheniumCatalysisPrimary (astronomy)Combinatorial chemistryOrganic chemistryMedicinal chemistryPhysicsAstronomyAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization MethodsSynthetic Organic Chemistry Methods