Fingolimod (FTY720) prevents chronic rejection of rodent cardiac allografts through inhibition of the RhoA pathway
Wei Chen, Wenhao Chen, Song Chen, Ahmed Uosef, Rafik M. Ghobrial, Małgorzata Kloc
Topics & Concepts
RHOAFingolimodDownregulation and upregulationTransplantationImmune systemActin cytoskeletonMedicineCell biologyCancer researchImmunologyBiologyPharmacologyMultiple sclerosisSignal transductionCellCytoskeletonInternal medicineGeneticsGeneBiochemistrySphingolipid Metabolism and SignalingPI3K/AKT/mTOR signaling in cancerNeuroinflammation and Neurodegeneration Mechanisms