Development and Validation of Sample Preparation and an HPLC Analytical Method for Dissolution Testing in Fed-State Simulated Gastric Fluid—Illustrating Its Application for Ibuprofen and Ketoconazole Immediate Release Tablets
Harsh S. Shah, Rusha Sardhara, Kajal Nahar, Ting Xu, Poonam Delvadia, Akhtar Siddiqui, Zongming Gao, Arzu Selen, Kenneth R. Morris
Topics & Concepts
ChromatographyAnalyteSample preparationSolubilityDissolutionChemistryReproducibilityIbuprofenPharmacologyOrganic chemistryPhysical chemistryMedicineDrug Solubulity and Delivery SystemsAnalytical Chemistry and ChromatographyAnalytical Methods in Pharmaceuticals