Azithromycin and Doxycycline Resistance Profiles of U.S. Mycoplasma genitalium Strains and Their Association with Treatment Outcomes
Gwendolyn E. Wood, Nicole Jensen, Sabina G. Astete, Jørgen Skov Jensen, George E. Kenny, Christine M. Khosropour, Catherine W. Gillespie, Lisa E. Manhart, Patricia A. Totten
Abstract
= 0.41) failure, demonstrating no relationship between DOX MICs and treatment efficacy. Given the rapid spread of AZM resistance and the emergence of quinolone resistance, the current second-line therapy, monitoring MICs and evaluating other potential treatments for M. genitalium will be critical.
Topics & Concepts
Mycoplasma genitaliumAzithromycinUrethritisCervicitisMedicineDoxycyclineInternal medicineMicrobiologyAntibacterial agentAntibioticsSexually transmitted diseaseChlamydia trachomatisGastroenterologyGynecologyVirologyBiologySyphilisHuman immunodeficiency virus (HIV)Reproductive tract infections researchGenital Health and DiseaseBlood groups and transfusion