Reduced Graphene Oxide Based Electrochemical Nonenzymatic Human Serum Glucose Sensor
Medha Gijare, Sharmila Chaudhari, Satish Ekar, Anil D. Garje
Abstract
Present work proposes green synthesis of reduced graphene oxide using lemon peel extract(vitamin-c) and its application as an electrochemical nonenzymatic human serum glucose sensor. Improved modified Hummer's method was preferred for the preparation of graphene oxide. X-ray diffraction (XRD), Ultraviolet-visible absorption spectroscopy (UV-Vis) and X-ray photon spectroscopy (XPS) analysis revealed the successful reduction of Graphene oxide (GO) using lemon peel extract. Field emission scanning electron microscopy (FESEM), Fourier transform infra-red spectroscopy (FTIR) and Raman spectroscopy supports the formation of reduced graphene oxide (rGO) nanosheets. The proposed glucose sensor exhibits high sensitivity of 1402 Acm -2 mM -1 (S/N=3) along with correlation coefficient of 0.9887 and low detection limit of 0.011 M. The sensor has detected glucose with RSD of 1.99% in human blood serum. The measured values are well agreed with the values obtained using professional glucose sensor used in hospitals.