Pseudorabies Virus Regulates the Extracellular Translocation of Annexin A2 To Promote Its Proliferation
Maoyang Weng, Zhenhua Guo, Qingxia Lu, Qianyue Jin, Yao Jiang, Fangyu Wang, Junqing Guo, Guangxu Xing, Songlin Qiao, Gaiping Zhang
Abstract
. Therefore, our studies reveal a novel strategy by which alphaherpesvirus modifies ANXA2 to promote its replication and highlight ANXA2 as a target in developing novel promising antivirus agents in viral therapy.
Topics & Concepts
BiologyPseudorabiesExtracellularCell biologyChromosomal translocationVirusVirologyGeneticsGeneS100 Proteins and AnnexinsVenomous Animal Envenomation and Studiesinterferon and immune responses