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Hydrophobic tag-based protein degradation: Development, opportunity and challenge

Qindi He, Xiaofei Zhao, Donglin Wu, Siming Jia, Canlin Liu, Zitian Cheng, Fei Huang, Yadong Chen, Tao Lu, Shuai Lü

2023European Journal of Medicinal Chemistry57 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryComputational biologyProtein degradationProteolysisDrug discoverySmall moleculeDegradation (telecommunications)Drug developmentCombinatorial chemistryDrugPharmacologyBiochemistryEnzymeComputer scienceBiologyMedicineTelecommunicationsProtein Degradation and InhibitorsPeptidase Inhibition and AnalysisUbiquitin and proteasome pathways
Hydrophobic tag-based protein degradation: Development, opportunity and challenge | Litcius