15 years of genome-wide association studies and no signs of slowing down
Ruth J. F. Loos
Abstract
Over the past 15 years, genome-wide association studies (GWASs) have generated a wealth of new information. Larger samples sizes, refined phenotypes and higher-resolution genome-screens will continue to drive gene discovery in years ahead. Meanwhile, GWAS loci are increasingly translated into new biology and opportunities for clinical care.
Topics & Concepts
Genome-wide association studyGenetic associationGenomeComputational biologyBiologyAssociation (psychology)PhenotypeGeneticsGeneSingle-nucleotide polymorphismGenotypePsychologyPsychotherapistGenetic Associations and EpidemiologyEpigenetics and DNA MethylationGenomics and Rare Diseases