<i>Lactobacillus rhamnosus</i> GG ameliorates deoxynivalenol-induced kidney oxidative damage and mitochondrial injury in weaned piglets
Kaidi Ma, Yongsong Bai, Jibo Li, Zhongshuai Ren, Jianping Li, Jing Zhang, Anshan Shan
Abstract
< 0.05), and LGG could improve mitochondrial ultrastructural abnormalities and mitochondrial dysfunction. In addition, LGG mitigated DON-induced mitochondrial fusion inhibition, and prevented DON-mediated mitochondrial autophagy. In conclusion, LGG play a protective role in DON-induced kidney toxicity, and dietary intervention may be a strategy to reduce mycotoxins.
Topics & Concepts
Lactobacillus rhamnosusOxidative stressOxidative damageOxidative phosphorylationMitochondrionKidneyMicrobiologyLactobacillusChemistryFood scienceBiologyPharmacologyBiochemistryEndocrinologyFermentationGenomics, phytochemicals, and oxidative stressPhytochemicals and Antioxidant ActivitiesMycotoxins in Agriculture and Food