A targeted near-infrared nanoprobe for deep-tissue penetration and imaging of prostate cancer
Mena Asha Krishnan, Kratika Yadav, Paul Roach, Venkatesh Chelvam
Abstract
tumour with sub-nanomolar affinity and high specificity, (ii) shows an excellent safety profile in primary cell lines in vitro and (iii) shows high penetrative capacity in a 3D prostate tumour model (∼450 μm tissue depth).
Topics & Concepts
Prostate cancerNanoprobePenetration (warfare)ProstateCancer researchChemistryCancerPathologyBiomedical engineeringMedicineMaterials scienceNanotechnologyInternal medicineNanoparticleEngineeringOperations researchNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsMass Spectrometry Techniques and Applications