A simple hydrogen peroxide-activatable Bodipy for tumor imaging and type I/II photodynamic therapy
Fangqing Ge, Sun Yujie, Yu Wang, Dan Yu, Zhijia Wang, Fabiao Yu, Bingran Yu, Hongbing Fu
Abstract
, further elevating the signal-to-background ratio (SBR) of imaging. Besides outstanding performance in tumor imaging, a prominent inhibition of tumor growth was observed. Given its simple molecular skeleton, this Bodipy photosensitizer is a competitive candidate for cancer theranostics.
Topics & Concepts
Hydrogen peroxidePhotodynamic therapyBODIPYCancer researchTumor microenvironmentCancer therapyMaterials scienceCancerMedicineChemistryTumor cellsInternal medicineFluorescenceOpticsBiochemistryOrganic chemistryPhysicsNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesCancer, Hypoxia, and Metabolism