A lysosome-targeted near-infrared fluorescent probe for imaging of acid phosphatase in living cells
Songtao Cai, Chang Liu, Xiaojie Jiao, Song He, Liancheng Zhao, Xianshun Zeng
Abstract
. The probe SHCy-P could also be used to detect and image endogenous ACP in lysosomes. In light of these prominent properties, we envision that SHCy-P will be an efficient optical imaging approach for investigating the ACP activity in disease diagnosis.
Topics & Concepts
LysosomeFluorescenceAcid phosphataseFluorescence-lifetime imaging microscopyOptical imagingChemistryBiophysicsBiochemistryBiologyOpticsEnzymePhysicsMolecular Sensors and Ion DetectionLuminescence and Fluorescent MaterialsSulfur Compounds in Biology