Hyaluronic acid-modified doxorubicin-covalent organic framework nanoparticles triggered pyroptosis in combinations with immune checkpoint blockade for the treatment of breast cancer
Shengsheng Zhao, Binglong Bai, Bingzi Zhu, Yuekai Cui, Wenhai Deng, Zuoliang Xie, Shuaibin Wang, Xiang Wang, Yiwen Mao, Yongyong Lu, Yingpeng Huang, Tao You, Weijian Sun, Xian Shen, Xufeng Lu
Topics & Concepts
PyroptosisHyaluronic acidDoxorubicinBlockadeBreast cancerCovalent bondChemistryCancer researchImmune checkpointHyaluronidaseNanoparticleImmune systemCancerMedicineNanotechnologyBiochemistryMaterials scienceApoptosisReceptorImmunologyProgrammed cell deathInternal medicineChemotherapyEnzymeOrganic chemistryAnatomyNanoplatforms for cancer theranosticsInflammatory Biomarkers in Disease PrognosisInflammasome and immune disorders