EZH2 inhibits senescence-associated inflammation and attenuates intervertebral disc degeneration by regulating the cGAS/STING pathway via H3K27me3
Jianrui Zheng, Zetao Ma, Pei Liu, Jiewen Wei, Shaoxiong Min, Ying Shan, Jianlin Zhang, Ye Li, Lixiang Xue, Zhen Tan, Deli Wang
Topics & Concepts
StingInflammationDegeneration (medical)SenescenceCell biologyCellular senescenceIntervertebral discCancer researchMedicineBiologyImmunologyAnatomyPathologyGeneticsGenePhenotypePhysicsThermodynamicsinterferon and immune responsesSpine and Intervertebral Disc PathologyBone and Joint Diseases