Polymer-lipid hybrid nanovesicle-enabled combination of immunogenic chemotherapy and RNAi-mediated PD-L1 knockdown elicits antitumor immunity against melanoma
Changrong Wang, Xiaoguang Shi, Huijuan Song, Chuangnian Zhang, Xiaoli Wang, Pingsheng Huang, Anjie Dong, Yumin Zhang, Deling Kong, Weiwei Wang
Topics & Concepts
Cancer researchImmunogenic cell deathGene knockdownRNA interferenceImmunotherapyDoxorubicinMelanomaImmune systemGene silencingBiologyImmunologyMedicineApoptosisChemotherapyRNAInternal medicineBiochemistryGeneImmunotherapy and Immune ResponsesCAR-T cell therapy researchRNA Interference and Gene Delivery