Molecular clarification of brainstem astroblastoma with EWSR1-BEND2 fusion in a 38-year-old man
Matthew Smith-Cohn, Zied Abdullaev, Kenneth Aldape, Martha Quezado, Marc K. Rosenblum, Chad Vanderbilt, Fausto J. Rodríguez, John Laterra, Charles G. Eberhart
Abstract
, may have a more critical functional role, at least in these regions. This unusual clinical scenario exemplifies the utility of methylome profiling and assessment of gene fusions in tumors of the central nervous system.
Topics & Concepts
BrainstemTemozolomideHistopathologySpinal cordPathologyBiologyMedicineNeuroscienceGliomaCancer researchGlioma Diagnosis and TreatmentOcular Oncology and TreatmentsHead and Neck Surgical Oncology