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Biotin receptor-targeting nanogels loaded with methotrexate for enhanced antitumor efficacy in triple-negative breast cancer in vitro and in vivo models

Samira Sadat Abolmaali, Sepideh Zarenejad, Younes Mohebi, Haniyeh Najafi, Sanaz Javanmardi, Mehdi Abedi, Ali Mohammad Tamaddon

2022International Journal of Pharmaceutics23 citationsDOI

Topics & Concepts

In vivoBiotinTriple-negative breast cancerPharmacologyPEG ratioChemistryPharmacokineticsDrug deliveryTargeted drug deliveryIn vitroDistribution (mathematics)IC50ToxicityCancer researchDrugBreast cancerMedicineCancerBiochemistryInternal medicineBiologyBiotechnologyMathematicsFinanceOrganic chemistryEconomicsMathematical analysisNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsGraphene and Nanomaterials Applications
Biotin receptor-targeting nanogels loaded with methotrexate for enhanced antitumor efficacy in triple-negative breast cancer in vitro and in vivo models | Litcius