Modulation of Gut Microbiota Composition and Short-Chain Fatty Acid Synthesis by Mogroside V in an <i>In Vitro</i> Incubation System
Ruiming Xiao, Wanci Liao, Guangjuan Luo, Zhenning Qin, Shuangyan Han, Ying Lin
Abstract
. Moreover, the synthesis of short-chain fatty acids, such as acetate, propionate, and butyrate, was increased by gut microbiota. According to ultraperformance liquid chromatography-mass spectrometry (UPLC-MS) analysis, MV was decomposed into secondary mogrosides, such as mogroside II/I and mogrol, by gut microbiota. Enhanced antioxidant abilities of the metabolites were found in the broth. The results suggested that MV, as a potential prebiotic, could benefit human health through its interaction with gut microbiota.
Topics & Concepts
ButyratePropionateBacteroidesGut floraPrevotellaPrebioticChemistryShort-chain fatty acidIncubationFood scienceLactobacillusIn vitroBiochemistryClostridiumFermentationBacteriaBiologyGeneticsGut microbiota and healthBiochemical Analysis and Sensing TechniquesProbiotics and Fermented Foods