Didymorenloids A and B, two polycyclic cyclopenta[<i>b</i>]fluorene-type alkaloids with anti-hepatoma activity from the mangrove endophytic fungus <i>Didymella</i> sp. CYSK-4
Yan Chen, Wencong Yang, Ge Zhu, Guisheng Wang, Tao Chen, Hang Li, Jie Yuan, Zhigang She
Abstract
Molecular networking guidance lead to the isolation of a new cyclopenta[ b ]fluorene-type alkaloid didymorenloid A (1), containing an unprecedented 6/5/6/5/13(6)/5/5/5-fused ring system, from the mangrove endophytic fungus Didymella sp. CYSK-4.
Topics & Concepts
MangroveChemistryFluoreneFungusAlkaloidStereochemistryPlant use of endophytic fungi in defenseBotanyOrganic chemistryBiologyEcologyPolymerMicrobial Natural Products and BiosynthesisPhytochemical Studies and BioactivitiesPlant-Microbe Interactions and Immunity