State of the Art for Diagnosis of Bacterial Vaginosis
Christina A. Muzny, Nuno Cerca, Jacob H. Elnaggar, Christopher M. Taylor, Jack D. Sobel, Barbara Van Der Pol
Abstract
hybridization (FISH), are specifically highlighted, in addition to multiplex nucleic acid amplification tests (NAATs), given their increasing use in clinical practice (NAATs) and research studies (16S rRNA gene sequencing, shotgun metagenomic sequencing, and FISH) regarding the vaginal microbiota and BV pathogenesis. We also provide a discussion of the strengths and weaknesses of current BV diagnostic tests and discuss future challenges in this field of research.
Topics & Concepts
Bacterial vaginosisMetagenomicsBiologyDysbiosisGardnerella vaginalisMicrobiologyBioinformaticsMicrobiomeGeneticsGeneReproductive tract infections researchSyphilis Diagnosis and TreatmentUrinary Tract Infections Management