Photoexcited Pd(<scp>ii</scp>) auxiliaries enable light-induced control in C(sp<sup>3</sup>)–H bond functionalisation
Milena L. Czyz, Geethika K. Weragoda, Tyra H. Horngren, Timothy U. Connell, Daniel E. Gómez, Richard A. J. O’Hair, Anastasios Polyzos
Abstract
Visible light irradiation of 8-aminoquinoline Pd(<sc>ii</sc>) complexes initiates photoinduced electron transfer with alkyl halides, affording C–H halogenation over C–C bond adducts. A method for inert C(sp<sup>3</sup>)–H bond halogenation (Br, Cl and I) is reported.
Topics & Concepts
HalogenationChemistryAdductIrradiationHalideAlkylMedicinal chemistryPhotochemistryVisible spectrumStereochemistryOrganic chemistryMaterials sciencePhysicsNuclear physicsOptoelectronicsCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSynthesis and Catalytic Reactions