For insights into the real world, consider real-world data
Sana Raoof, Razelle Kurzrock
Abstract
Randomized control trials (RCTs) are required before drug and device approvals and have contributed to patient safety, but they have also increased the cost and time of regulatory assessments. We propose that using real-world evidence to complement or, in some settings, to replace RCTs will accelerate delivery of new drugs to patients.
Topics & Concepts
Real world dataReal world evidenceRandomized controlled trialMedicineComplement (music)Clinical trialIntensive care medicineComputer scienceRisk analysis (engineering)Data scienceInternal medicineBiologyPhenotypeBiochemistryGeneComplementationStatistical Methods in Clinical TrialsHealth Systems, Economic Evaluations, Quality of LifeMeta-analysis and systematic reviews