Induction of the activating transcription factor-4 in the intratumoral CD8+ T cells sustains their viability and anti-tumor activities
Zhen Lu, Eun‐Ah Bae, Ioannis I. Verginadis, Hongru Zhang, Christina Cho, Noreen McBrearty, Subin S. George, J. Alan Diehl, Constantinos Koumenis, Linda M. Bradley, Serge Y. Fuchs
Topics & Concepts
ATF4Cytotoxic T cellTumor microenvironmentCD8Immune systemCancer researchCTL*BiologyImmunologyIn vitroCHOPBiochemistryLymphomaImmune Cell Function and InteractionT-cell and B-cell ImmunologyCAR-T cell therapy research