First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure
Stefan Zwirner, Anan Abu Rmilah, Sabrina Klotz, Bent Pfaffenroth, Philip Kloevekorn, Athina Anastasia Moschopoulou, Svenja Schuette, Mathias Haag, Roland Selig, Kewei Li, Wei Zhou, Erek Nelson, Antti Poso, Harvey Chen, Bruce Amiot, Jia Yao, Anna Minshew, Gregory J. Michalak, Wei Cui, Elke Rist, Thomas Longerich, Birgit Jung, Philipp Felgendreff, Omelyan Trompak, Prem K. Premsrirut, Katharina Gries, Thomas Muerdter, Georg Heinkele, Torsten Wüestefeld, David J. Shapiro, Markus Weissbach, Alfred Koenigsrainer, Bence Sipos, Eiso AB, Magdalena Ortiz Zacarias, Stephan Theisgen, Nicole Gruenheit, Saskia Biskup, Matthias Schwab, Wolfgang Albrecht, Stefan Laufer, Scott L. Nyberg, Lars Zender
Topics & Concepts
Liver regenerationLiver transplantationHepatocyteBiologyHepatectomyRegeneration (biology)Clinical trialLiver diseaseChronic liver diseasePharmacologyDrug developmentTransplantationInternal medicineCancer researchDrugPathologyBioinformaticsMedicineSurgeryCirrhosisIn vitroCell biologyBiochemistryResectionLiver physiology and pathologyCancer Mechanisms and TherapyOrgan Transplantation Techniques and Outcomes