Arctigenin: pharmacology, total synthesis, and progress in structure modification
Dan Wu, Lili Jin, Xing Huang, Hao Deng, Qing‐Kun Shen, Zhe‐Shan Quan, Changhao Zhang, Hong-Yan Guo
Abstract
is a prevalent medicinal herb and a health supplement that is commonly used in Asia. Over the last few decades, the bioactive component arctigenin has attracted the attention of researchers because of its anti-inflammatory, antioxidant, immunomodulatory, multiple sclerosis fighting, antitumor, and anti-leukemia properties. After summarising the research and literature on arctigenin, this study outlines the current status of research on pharmacological activity, total synthesis, and structural modification of arctigenin. The purpose of this study is to assist academics in obtaining a more comprehensive understanding of the research progress on arctigenin and to provide constructive suggestions for further investigation of this useful molecule.