Modelling frontotemporal dementia using patient-derived induced pluripotent stem cells
Georgie Lines, Jackie M. Casey, Elisavet Preza, Selina Wray
Topics & Concepts
C9orf72Frontotemporal dementiaInduced pluripotent stem cellBiologyReprogrammingTrinucleotide repeat expansionHaploinsufficiencyNeurosciencePhenotypeGeneticsCell biologyDementiaDiseaseCellGenePathologyMedicineAlleleEmbryonic stem cellAmyotrophic Lateral Sclerosis ResearchPluripotent Stem Cells ResearchPrion Diseases and Protein Misfolding