PRMT4 promotes ferroptosis to aggravate doxorubicin-induced cardiomyopathy via inhibition of the Nrf2/GPX4 pathway
Yilong Wang, Shu Yan, Xuemei Liu, Fei Deng, Pengchao Wang, Liuye Yang, Lizhi Hu, Kai Huang, Jiangui He
Topics & Concepts
GPX4Cell biologyAutophagyTranscription factorBiologyProgrammed cell deathCell cultureGene silencingOxidative stressChemistryCancer researchMolecular biologyApoptosisBiochemistryGlutathione peroxidaseSuperoxide dismutaseGeneGeneticsCancer-related gene regulationPeptidase Inhibition and AnalysisGDF15 and Related Biomarkers