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Shining a Light on the Advances, Challenges and Realisation of Utilising Photoredox Catalysis in Pharmaceutical Development

Emily E. Callard‐Langdon, Alan Steven, Rachel J. Kahan

2023ChemCatChem18 citationsDOI

Abstract

Abstract Photoredox catalysis has advanced significantly over the last fifteen years, with improvements in technology facilitating implementation in both academic and industrial settings. Despite these advances, the uptake of photoredox catalysis in pharmaceutical development and manufacture has been slow, in part due to the challenge of developing a robust, transferable process. This perspective provides insight on the successes and difficulties encountered when applying photoredox catalysis to pharmaceutical development. It is hoped greater understanding of the challenges faced by the pharmaceutical industry will inform future research and encourage collaboration.

Topics & Concepts

Photoredox catalysisPharmaceutical industryRealisationProcess (computing)Process developmentNanotechnologyBiochemical engineeringProcess managementEngineeringComputer scienceChemistryMedicineCatalysisMaterials sciencePhotocatalysisOrganic chemistryPharmacologyOperating systemPhysicsQuantum mechanicsRadical Photochemical ReactionsAdvanced Photocatalysis TechniquesInnovative Microfluidic and Catalytic Techniques Innovation
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