A DS2-specific flavonoid-based probe with a unique dual-emissive response to human serum albumin
Yingying Huang, Taoyuze Lv, Tianyi Qin, Zhongyong Xu, Lei Wang, Bin Liu
Abstract
The hydroxyl substituent in flavonoids can cause the binding site to change from DS1 to DS2 and restore the ESIPT process of flavonoids, thereby leading to a unique dual-emissive response towards human serum albumin.
Topics & Concepts
FlavonoidSubstituentChemistryHuman serum albuminSerum albuminAlbuminBiochemistryStereochemistryAntioxidantProtein Interaction Studies and Fluorescence AnalysisLanthanide and Transition Metal ComplexesElectron Spin Resonance Studies