Biomimetic carrier-free nanoparticle delivers digoxin and doxorubicin to exhibit synergetic antitumor activity in vitro and in vivo
Zhe Zhang, Yingying Wang, Qian Ma, Shaolu Zhang, Hong-Yan Liu, Baoquan Zhao, Rui Liu, Wei Wang, Bo Du, Yuxu Zhong, Dexin Kong
Topics & Concepts
DoxorubicinIn vivoDU145A549 cellChemistryPharmacologyApoptosisCancer researchCell cultureIn vitroCancer cellCell biologyCancerBiologyBiochemistryChemotherapyLNCaPGeneticsBiotechnologyNanoparticle-Based Drug DeliveryRadiation Therapy and DosimetryPARP inhibition in cancer therapy