Cu(I) and Cu(II) Complexes Based on Lonidamine-Conjugated Ligands Designed to Promote Synergistic Antitumor Effects
Fabio Del Bello, Maura Pellei, Luca Bagnarelli, Carlo Santini, Gianfabio Giorgioni, Alessandro Piergentili, Wilma Quaglia, Chiara Battocchio, Giovanna Iucci, Irene Schiesaro, Carlo Meneghini, Iole Venditti, Nitya Ramanan, Michele De Franco, Paolo Sgarbossa, Cristina Marzano, Valentina Gandin
Abstract
induced cancer cell death by means of an apoptosis-alternative cell death.
Topics & Concepts
ChemistryCisplatinX-ray absorption fine structureConjugated systemCopperStereochemistryApoptosisCombinatorial chemistrySpectroscopyOrganic chemistryBiochemistryChemotherapyPolymerMedicineQuantum mechanicsPhysicsSurgeryMetal complexes synthesis and propertiesSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds