Investigation of the MDM2-binding potential of de novo designed peptides using enhanced sampling simulations
Olanrewaju Ayodeji Durojaye, Abeeb Abiodun Yekeen, Mukhtar Oluwaseun Idris, Nkwachukwu Oziamara Okoro, Arome Solomon Odiba, Bennett C. Nwanguma
Topics & Concepts
Molecular dynamicsIn silicoPeptideMdm2BiophysicsRational designComputational biologyChemistryBiologyBiochemistryApoptosisComputational chemistryGeneticsGeneProtein Structure and DynamicsChemical Synthesis and AnalysisRNA and protein synthesis mechanisms