Injectable and <i>In Situ</i>-Formable Thiolated Chitosan-Coated Liposomal Hydrogels as Curcumin Carriers for Prevention of <i>In Vivo</i> Breast Cancer Recurrence
Riwang Li, Zhen Lin, Qian Zhang, Yuhui Zhang, Yi Liu, Yang Lyu, Xinyang Li, Changren Zhou, Gang Wu, Ningjian Ao, Li-Hua Li
Abstract
-formable, and thermosensitive CSSH/Cur-Lip gel can be designed as a promising novel drug delivery vehicle to be used as carriers for local accurate and sustained drug delivery to minimize burst release and as tissue engineering scaffolds for tissue regeneration after tumor resection.
Topics & Concepts
CurcuminSelf-healing hydrogelsIn vivoChitosanMaterials scienceLiposomeDrug deliveryBioavailabilityBiomedical engineeringCytotoxicityControlled releasePharmacologyIn vitroChemistryNanotechnologyMedicineBiochemistryPolymer chemistryBiologyBiotechnologyNanoparticle-Based Drug DeliveryHydrogels: synthesis, properties, applicationsAdvanced Drug Delivery Systems