A microfluidic chip with a serpentine channel enabling high-throughput cell separation using surface acoustic waves
Shupeng Ning, Shuchang Liu, Yunjie Xiao, Guanyu Zhang, Weiwei Cui, Mark A. Reed
Abstract
) without losing separation purity or cell recovery. The serpentine microfluidic design provides a compatible solution for high-throughput separation, which can synergize with other functional designs to improve device performance. Further, its advantages such as low cost, high biocompatibility, label-free separation and ability to integrate with on-chip biosensors are promising for clinical utility in point-of-care diagnostic platforms.
Topics & Concepts
MicrofluidicsThroughputChannel (broadcasting)Separation (statistics)Microfluidic chipChipMaterials scienceSurface acoustic waveNanotechnologySeparation methodPoint (geometry)Electronic engineeringAcousticsComputer scienceOptoelectronicsComputer hardwareChemistryChromatographyEngineeringTelecommunicationsPhysicsWirelessMathematicsMachine learningGeometryMicrofluidic and Bio-sensing TechnologiesMicrofluidic and Capillary Electrophoresis ApplicationsNanopore and Nanochannel Transport Studies