Sovleplenib (HMPL-523), a novel Syk inhibitor, for patients with primary immune thrombocytopenia in China: a randomised, double-blind, placebo-controlled, phase 1b/2 study
Xiaofan Liu, Hu Zhou, Yu Hu, Jie Yin, Junmin Li, Wen-Ming Chen, Ruibin Huang, Yuping Gong, Chengwei Luo, Heng Mei, Bingjie Ding, Chengyuan Gu, Huiping Sun, Yun Leng, Dexiang Ji, Yan Li, Hongyan Yin, Haiyan Shi, Keyan Chen, Jian Wang, Songhua Fan, Weiguo Su, Renchi Yang
Topics & Concepts
MedicinePlaceboTolerabilityClinical endpointInternal medicineSplenectomyAdverse effectIntention-to-treat analysisGastroenterologyNeutropeniaClinical trialSurgeryChemotherapySpleenPathologyAlternative medicinePlatelet Disorders and TreatmentsMast cells and histamineHemophilia Treatment and Research