<i>De novo</i> structural determination of oligosaccharide isomers in glycosphingolipids using logically derived sequence tandem mass spectrometry
Chia Yen Liew, Chieh‐Kai Chan, Shih‐Pei Huang, Yu‐Ting Cheng, Shang‐Ting Tsai, Hsu Chen Hsu, Cheng‐Chung Wang, Chi‐Kung Ni
Abstract
Despite the importance of carbohydrates in biological systems, structural determination of carbohydrates remains difficult because of the large number of isomers.
Topics & Concepts
OligosaccharideChemistryMass spectrometryTandem mass spectrometryMonosaccharideGlycanAnomerFast atom bombardmentChromatographyStereochemistryBiochemistryGlycoproteinGlycosylation and Glycoproteins ResearchCarbohydrate Chemistry and SynthesisGenomics and Phylogenetic Studies