Visible light-mediated copper catalyzed regioselective diamination of terminal alkynes at room temperature: a facile synthesis of substituted imidazo[1,2-α]pyridines
Vaibhav Pramod Charpe, Mahima Gupta, Kuo Chu Hwang
Abstract
We have developed a protocol for the regioselective synthesis of substituted imidazo[1,2-α]pyridines at room temperature using low-energy visible light, inexpensive CuCl as a catalyst, readily available starting materials, mild reaction conditions, and O 2 as a green oxidant.
Topics & Concepts
RegioselectivityChemistryCatalysisCopperPyridineAminopyridinesTerminal (telecommunication)Combinatorial chemistryOxygenAminationMedicinal chemistryPhotochemistryOrganic chemistryComputer scienceTelecommunicationsCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques