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Capturing electronic substituent effect with effective atomic orbitals

Gerard Comas‐Vilà, Pedro Salvador

2025Physical Chemistry Chemical Physics15 citationsDOIOpen Access PDF

Abstract

The occupation of the effective atomic orbitals (eff-AOs) of the carbon atoms in the aromatic ring is used to derive accurate descriptors of the inductive and resonance effects exerted by substituents in benzene derivatives.

Topics & Concepts

SubstituentAtomic orbitalComputational chemistryChemistryStereochemistryPhysicsQuantum mechanicsElectronSynthesis and Properties of Aromatic CompoundsAdvanced Chemical Physics StudiesOrganic Chemistry Cycloaddition Reactions
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