By restoring autophagic flux and improving mitochondrial function, corosolic acid protects against Dox-induced cardiotoxicity
Yan Che, Zhaopeng Wang, Yuan Yuan, Heng Zhou, Hai‐Ming Wu, Shasha Wang, Qizhu Tang
Topics & Concepts
TFEBCardiotoxicityAMPKPharmacologyAutophagyOxidative stressChemistryPI3K/AKT/mTOR pathwayProtein kinase BApoptosisMedicineInternal medicineProtein kinase ABiochemistryKinaseToxicityAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolismNeutrophil, Myeloperoxidase and Oxidative Mechanisms